51-01 BIOLOGY (GENERAL)
Jun 29, 2008 -- Additions to the NASA scientific and technical information knowledge base
Title:
Effects of Simulated Weightlessness on Cellular Morphology, Cell Multiplication and Cell Cycle of MG-63 Cells
Document ID:
20080020465
Report #:
None
Sales Agency:
Other Sources Copyright
Author(s):
Wang, Pan (Institute of Space Medico-Engineering) Zhang, Shu (Institute of Space Medico-Engineering) Wang, Bing (Institute of Space Medico-Engineering) Sun, Xi-qing (Institute of Space Medico-Engineering) Geng, Jie (Institute of Space Medico-Engineering) Gao, Yuan (Institute of Space Medico-Engineering)
Journal:
Space Medicine and Medical Engineering, Volume 20, No. 6, Page: 406-409
Published:
20071201
Source:
Institute of Space Medico-Engineering (Beijing, China)
Pages:
--
Contract #:
None
Abstract:
Proposed to investigate the effects of simulated weightlessness on cell area, cell multiplication and cell cycle of MG-63 cells. The rotating clinostat was used to simulate weightlessness. The change of cell area was measured with image processing and analysis soft (Image J). Cell growth curve was measured with cytometry. The change of cell cycle was examined with a flow cytometer. Compared with control group, the cell area of cell line MG-63 in 24 h,36 h and 48 h durations of rotating group decreased significantly (P<0.05). Compared with 12 h duration, the cell area in 24 h, 36 h and 48 h durations of rotating group decreased significantly (P<0.05). But in control group, cell area of all 4 experimental durations showed no significant difference among each other. Compared with control group, cell growth curve revealed that cell multiplication was inhibited in rotating group. Compared with control group, the cell cycles of cell line MG-63 in 12 h, 36 h, 48 h sections of rotating group did not change significantly, but the cell in 24 h duration of rotating group was decreased significantly (P<0.05) in G0 + G1 phase and increased significantly (P<0.05 ) in S phase. Simulated weightlessness in rotating clinostat may lead cell area of cell line MG-63 in 24 h, 36 h and 48 h durations to be decreased. Cell multiplication is inhibited in 12 h, 24 h, 36 h and 48 h durations. The conversion of cell from S phase to G2 phase is inhibited in 24 h duration.
Language:
Chinese
Title:
A Study of Computer Detecting Methods for Animal Swimming Experiment
Document ID:
20080020468
Report #:
None
Sales Agency:
Other Sources Copyright
Author(s):
ZHANG, Yu (Institute of Space Medico-Engineering) CHEN, Shang-guang (Institute of Space Medico-Engineering) LI, Da-chen (Institute of Space Medico-Engineering)
Journal:
Space Medicine and Medical Engineering, Volume 20, No. 6, Page: 436-440
Published:
20071201
Source:
Institute of Space Medico-Engineering (Beijing, China)
Pages:
--
Contract #:
None
Abstract:
Proposed to study a a computer-based testing system for an animal swimming test with mice by integrating the knowledge of computer science and image processing with that of traditional Chinese medicine. The moving objects of the swimming mice were extracted by computer and the gained information was analyzed. The computer controlled animal swimming testing system was developed and a new index-evaluation method which is more sensitive to mice swimming resistance were established. The computer detecting method yielded higher automation and more samples to be detected, obtained more detecting indices and more comprehensive and accurate data providing a new effective measure for the animal swimming experiment in the pharmacological research of Chinese medicinal herbs.
Language:
Chinese
Title:
Effects of Carbon Monoxide on Cerebella Gene Expression in Mice
Document ID:
20080020469
Report #:
None
Sales Agency:
Other Sources Copyright
Author(s):
LI, Shu-guang (China Astronaut Research and Training Center) LIANG, Hong (Institute of Space Medico-Engineering) ZHANG, Heng-tai (Institute of Space Medico-Engineering) HE, Xin-xing (Institute of Space Medico-Engineering)
Journal:
Space Medicine and Medical Engineering, Volume 20, No. 6, Page: 418-421
Published:
20071201
Source:
China Astronaut Research and Training Center (Beijing, China)
Pages:
--
Contract #:
None
Abstract:
Proposed to investigate the effect of carbon monoxide (CO) on cerebella gene expression in mice. Suppression subtractive hybridization (SSH) technique was applied to screen differentially expressed gene in cerebella of mice that breathed 750 mg/m3 CO for 72 h. Twenty differentially expressed sequence tags found after exposure to 750 mg/m3 CO for 72 h were cloned and determined. CO toxicity may influence gene expression related to significant cell signs, transduction, metabolism, spermiogenesis, immunity and more.
Language:
Chinese
Title:
Protective Effects of Cudrania Tricuspidata Polysaccharides and Lycium Barbarium Polysaccharides on the Immune Function of Tail-Suspended Mice
Document ID:
20080020474
Report #:
None
Sales Agency:
Other Sources Copyright
Author(s):
Song, Jin-ping (Institute of Space Medico-Engineering) Zhang, Hong-yu (Institute of Space Medico-Engineering) Qu, Li-na (Institute of Space Medico-Engineering) Yang, Fen (Institute of Space Medico-Engineering) Liu, Shao-fang (Institute of Space Medico-Engineering) Wang, Hong-hui (Institute of Space Medico-Engineering) Liu, Yue (Institute of Space Medico-Engineering) Xiong, Jiang-hui (Institute of Space Medico-Engineering)
Journal:
Space Medicine and Medical Engineering, Volume 20, No. 6, Page: 402-405
Published:
20071201
Source:
Institute of Space Medico-Engineering (Beijing, China)
Pages:
--
Contract #:
None
Abstract:
Proposed to study the protective effects of Cudrania tricuspidata polysaccharides (CPS) and Lycium barbarium polysaccharides (LBP) on the cellular immune function in tail-suspended mice. Two dosages of CPS and LBP were orally administered to tail-suspended mice, respectively. Splenic T lymphocyte proliferation was determined by MTS colorimetric assay and cytokines production in supernatants obtained from cultured spleen cells after stimulation with ConA were detected by ELISA assay. Splenic T lymphocyte proliferation and the levels of IL-2 and IFN-gamma decreased significantly in tail-suspended mice 7 d later, which could be enhanced by administration of CPS. CPS has protective effects on cellular immunity of tail-suspended mice in simulated microgravity.
Language:
Chinese
51-02 BIOCHEMISTRY
Jun 29, 2008 -- Additions to the NASA scientific and technical information knowledge base
No records are available for this topic on this date.
52-01 AEROSPACE MEDICINE
Jun 29, 2008 -- Additions to the NASA scientific and technical information knowledge base
Title:
Space Medicine and Medical Engineering, Volume 20, No. 6
Document ID:
20080020461
Report #:
CN-11-2774/R
Sales Agency:
Other Sources Copyright
Author(s):
Wang, Yong-zhi (Institute of Space Medico-Engineering) Grigoriev, A. I. (Institute of Space Medico-Engineering) White, Ronald J. (Institute of Space Medico-Engineering) Wang, Xi-ji (Institute of Space Medico-Engineering) Yu, Meng-sun (Institute of Space Medico-Engineering) QI Fa-ren (Institute of Space Medico-Engineering) Wei, Jin-he (Institute of Space Medico-Engineering) Chen, Shan-guang (Institute of Space Medico-Engineering) Wang, Xian-min (Institute of Space Medico-Engineering) Bai, Jing (Institute of Space Medico-Engineering) Bai, Yan-qiang (Institute of Space Medico-Engineering) Sun, Xi-qing (Institute of Space Medico-Engineering) Hong, Feng (Institute of Space Medico-Engineering) Su Hong-yu (Institute of Space Medico-Engineering) Jiang, Shi-zhong (Institute of Space Medico-Engineering)
Published:
20071201 Publisher: Institute of Space Medico-Engineering
Source:
Institute of Space Medico-Engineering (Beijing, China)
Pages:
100
Contract #:
None
Abstract:
Topics covered include: Identification of Model Parameters Basing on Matched Processing between Simulated and Recorded sEMG Signals; Cardiovascular Responses to Lower Body Negative Pressure (LBNP) in Healthy Females of Different Physical Fitness; Protective Effects of Cudrania Tricuspidata Polysaccharides and Lycium Barbarium; Polysaccharides on the Immune Function of Tail-suspended Mice; Effects of Simulated Weightlessness on Cellular Morphology, Cell Multiplication and Cell Cycle of MG-63 Cell; Effects of Heat Stress on Exercise Tolerance, Serum Testosterone and Cortisol; Concentrations in Tail-Suspended Rats; Alteration of Fos Expression in Periaqueductal Gray of Rat after 2 Weeks Simulated Weightlessness; Effects of Carbon Monoxide on Cerebella Gene Expression in Mice; Design of a Head-up Tilt Experimental System for Measuring Head Blood Pressure and Its Dynamic Process; The Design and Experiment of Solid Polymer Electrolyte Water Electrolytic Cell; A Study of Metal Oxide CO2 Absorbents; A Study of Computer Detecting Methods for Animal Swimming Experiment; Facial Skin Temperature Increase Induced by Local Cooling of Jugular Vessel and Its Interpretation Using Systematic Bioheat Transfer Mechanism; EEG Study on Transcutaneous Electrical Acupoint Stimulation as a Fatigue Countermeasure; Estimation of Mean Trabecular Bone Spacing Using Cepstrum Method Based on Inverse Filter; Detrended Fluctuation Analysis of Pulse Rate Variability Signals of Coronary Disease Patients; Automatic Sleep Stage Classification Based on Hilbert-Huang Transform Method of EEG; and Progress in Fabrication of Neural Probe Microelectrodes and Its Application in Brain-Machine Interface.
Language:
English
Title:
Estimation of Mean Trabecular Bone Spacing Using Cepstrum Method Based on Inverse Filter
Document ID:
20080020462
Report #:
None
Sales Agency:
Other Sources Copyright
Author(s):
Huang, Kai (Institute of Space Medico-Engineering) Ta, De-an (Institute of Space Medico-Engineering) Wang, Wei-qi (Institute of Space Medico-Engineering) Lawrence, HL (Institute of Space Medico-Engineering)
Journal:
Space Medicine and Medical Engineering, Volume 20, No. 6, Page: 451-454
Published:
20071201
Source:
Institute of Space Medico-Engineering (Beijing, China)
Pages:
--
Contract #:
None
Abstract:
Proposed to explore the feasibility of estimating mean trabecular bone spacing (MTBS) by the improved cepstrum method. The improved cepstrum method based on an inverse filter is proposed in this paper. In order to test its performance, simulations were performed and bovine tibia cancellous bone specimens in vitro were used in our experiments. It is indicated that the improved cepstrum method can minimize the influence of transducer impulse response and tissue scatterer properties. It also can be easily implemented with little computation. Compared with traditional cepstrum, the improved cepstrum method has a more accurate MTBS estimate because of its less sensitivity to the variety of MTBS, diffuse scattering and noise.
Language:
Chinese
Title:
EEG Study on Transcutaneous Electrical Acupoint Stimulation as a Fatigue Countermeasure
Document ID:
20080020463
Report #:
None
Sales Agency:
Other Sources Copyright
Author(s):
DONG, Jie (Institute of Space Medico-Engineering) LI, Lu-ming (Tsinghua Univ.) HAO, Hong-wei (Institute of Space Medico-Engineering) CHEN, Zhao-yang (Institute of Space Medico-Engineering)
Journal:
Space Medicine and Medical Engineering, Volume 20, No. 6, Page: 447-450
Published:
20071201
Source:
Institute of Space Medico-Engineering (Beijing, China)
Pages:
--
Contract #:
None
Abstract:
Proposed to investigate the action of transcutaneous electrical acupoint stimulation to reduce fatigue, and to evaluate the countermeasure effect. Twelve-channel EEG signals (F3, F2, F4, C3, Cz, C4, P3, Pz, P4, O1, Oz, O21) were recorded in 9 young, healthy male volunteers under three conditions: normal, fatigue and after transcutaneous electrical acupoint stimulation. G values, the average power spectral densities, of delta, theta, alpha, beta EEG bands were calculated to analyze the EEG effect after transcutaneous electrical acupoint stimulation. G values of delta, theta, alpha, beta EEG bands and imbalance of G values of alpha EEG bands increased during fatigue, compared with those in the normal condition. G values of delta, theta, alpha, beta EEG bands and imbalance of G values of alpha EEG bands decreased after transcutaneous electrical acupoint stimulation. Transcutaneous electrical acupoint stimulation provides a positive countermeasure effect for fatigue as revealed by EEG.
Language:
Chinese
Title:
Effects of Simulated Weightlessness on Cellular Morphology, Cell Multiplication and Cell Cycle of MG-63 Cells
Document ID:
20080020465
Report #:
None
Sales Agency:
Other Sources Copyright
Author(s):
Wang, Pan (Institute of Space Medico-Engineering) Zhang, Shu (Institute of Space Medico-Engineering) Wang, Bing (Institute of Space Medico-Engineering) Sun, Xi-qing (Institute of Space Medico-Engineering) Geng, Jie (Institute of Space Medico-Engineering) Gao, Yuan (Institute of Space Medico-Engineering)
Journal:
Space Medicine and Medical Engineering, Volume 20, No. 6, Page: 406-409
Published:
20071201
Source:
Institute of Space Medico-Engineering (Beijing, China)
Pages:
--
Contract #:
None
Abstract:
Proposed to investigate the effects of simulated weightlessness on cell area, cell multiplication and cell cycle of MG-63 cells. The rotating clinostat was used to simulate weightlessness. The change of cell area was measured with image processing and analysis soft (Image J). Cell growth curve was measured with cytometry. The change of cell cycle was examined with a flow cytometer. Compared with control group, the cell area of cell line MG-63 in 24 h,36 h and 48 h durations of rotating group decreased significantly (P<0.05). Compared with 12 h duration, the cell area in 24 h, 36 h and 48 h durations of rotating group decreased significantly (P<0.05). But in control group, cell area of all 4 experimental durations showed no significant difference among each other. Compared with control group, cell growth curve revealed that cell multiplication was inhibited in rotating group. Compared with control group, the cell cycles of cell line MG-63 in 12 h, 36 h, 48 h sections of rotating group did not change significantly, but the cell in 24 h duration of rotating group was decreased significantly (P<0.05) in G0 + G1 phase and increased significantly (P<0.05 ) in S phase. Simulated weightlessness in rotating clinostat may lead cell area of cell line MG-63 in 24 h, 36 h and 48 h durations to be decreased. Cell multiplication is inhibited in 12 h, 24 h, 36 h and 48 h durations. The conversion of cell from S phase to G2 phase is inhibited in 24 h duration.
Language:
Chinese
Title:
A Study of Metal Oxide CO2 Absorbents
Document ID:
20080020467
Report #:
None
Sales Agency:
Other Sources Copyright
Author(s):
YU, Qing-ni (China Astronaut Research and Training Center) ZHAO, Cheng-jian (Institute of Space Medico-Engineering) WEI, Wei (Institute of Space Medico-Engineering)
Journal:
Space Medicine and Medical Engineering, Volume 20, No. 6, Page: 432-435
Published:
20071201
Source:
China Astronaut Research and Training Center (Beijing, China)
Pages:
--
Contract #:
None
Abstract:
Proposed to develop a regenerable metal oxide CO2 removal technology and to prepare a metal oxide absorbent for absorbing CO2. Several formulations were selected to form metal oxide absorbent pellets, their performances of CO2 absorption and regeneration were then tested respectively. The results demonstrated that the metal oxide absorbent we prepared has good CO2 absorption and regeneration performances (up to 0.2 g/mL CO2 capacity per volume unit, crush strength of 4 kg and bulk density of 1.53 g/mL). The metal oxide absorbent we prepared has the potential for application in regenerable portable life support system.
Language:
Chinese
Title:
Automatic Sleep Stage Classification Based on Hilbert-Huang Transform Method of EEG
Document ID:
20080020470
Report #:
None
Sales Agency:
Other Sources Copyright
Author(s):
Li, Gu (Institute of Space Medico-Engineering) Fan, Ying-le (Institute of Space Medico-Engineering) Li, Yi (Institute of Space Medico-Engineering) PANG, Quan (Institute of Space Medico-Engineering)
Journal:
Space Medicine and Medical Engineering, Volume 20, No. 6, Page: 458-463
Published:
20071201
Source:
Institute of Space Medico-Engineering (Beijing, China)
Pages:
--
Contract #:
None
Abstract:
Proposed to present a new application of the Hilbert-Huang transform method for automatic sleep stage classification. Instantaneous frequencies of sleep EEG with physical meaning and energy-frequency distribution used as feature parameters for each stage were computed with the Hilbert-Huang transform. Finally, the pattern recognition method of nearest neighbors was applied to optimal classification. Five hundred and sixty samples were picked from sleep EEG, and classification was made. The mean rate of accuracy was as high as 81.7%. Automatic sleep stage classification can be made effectively from features of sleep EEG by the Hilbert-Huang transform.
Language:
English
Title:
Design of a Head-up Tilt Experimental System for Measuring Head Blood Pressure and Its Dynamic Process
Document ID:
20080020473
Report #:
None
Sales Agency:
Other Sources Copyright
Author(s):
LIU, Yan-yong (Institute of Space Medico-Engineering) YU, Meng-sun (Air Force Inst. of Aviation Medicine) XIANG, Hai-yan (Institute of Space Medico-Engineering) JI, Jun (Institute of Space Medico-Engineering) Li, Yin-hua (Institute of Space Medico-Engineering) QIN, Yu-fei (Institute of Space Medico-Engineering)
Journal:
Space Medicine and Medical Engineering, Volume 20, No. 6, Page: 422-426
Published:
20071201
Source:
Institute of Space Medico-Engineering (Beijing, China)
Pages:
--
Contract #:
None
Abstract:
Proposed to design a head-up tilt (HUT) experimental system which is capable of measuring head blood pressure and its dynamic process, to enhance the efficiency of a HUT experiment. The head blood pressure was calculated by the individual-calibrated pulse wave transit time (PWTT) measured from the B point of the impedance cardiography (ICG) to the beginning point of the superficial temporal artery pulse wave. Based on the improved tilt bed, the HUT experimental system was designed to detect the dynamic blood pressure, ECG, phonocardiogram (PCG), respiration and ICG continuously. Finally, the system performance was examined by HUT experiments of three volunteers. Head blood pressure was calibrated with individual precise PWTT. The system detected physiological signals continuously and stably during HUT experiments and our preliminary results presented the minimum value, dynamic regulating process and overall level of head blood pressure. The system can exactly describe continuous, dynamic and transient process of head blood pressure during HUT experiments, which will provide more information about the regulation function of the cardiovascular system. It is possible to study the instant responses of the pilot to + Gz stresses in high-perfomance aircraft.
Language:
Chinese
Title:
Detrended Fluctuation Analysis of Pulse Rate Variability Signals of Coronary Disease Patients
Document ID:
20080020475
Report #:
None
Sales Agency:
Other Sources Copyright
Author(s):
Zhao, Hai-yong (Institute of Space Medico-Engineering) Qiu, Yi-hong (Institute of Space Medico-Engineering) Hu, Si-jun (Institute of Space Medico-Engineering) Zhu, Yi-sheng (Institute of Space Medico-Engineering)
Journal:
Space Medicine and Medical Engineering, Volume 20, No. 6, Page: 455-457
Published:
20071201
Source:
Institute of Space Medico-Engineering (Beijing, China)
Pages:
--
Contract #:
None
Abstract:
Nonlinear method was applied to the analysis of pulse rate variability (PRV) signal of healthy people and coronary disease patients to find the different features, which can be used to detect coronary disease invasively and monitor the process of the disease. Pulse waves of the healthy people and patients (18 subjects in each group) were sampled by photoplethysmographic (PPG) sensor. The detrended fluctuation analysis algorithm was applied to PRV series which extracted from PPG signals, and the scaling exponents of the two groups of signals were obtained. The average scaling exponents of the patients, i.e. short term alpha(exp 1) long term alpha(exp 2), and whole process alpha, were significantly lower than those of the healthy subjects. Detrended fluctuation analysis algorithm was applied to the PRV signal of the healthy subjects and coronary disease patients. It was found that the average scaling exponents of the patients, alpha(exp 1) , alpha(exp 2) and alpha, are significantly different from those of the healthy people. These findings suggest that a nonlinear index could be used to detect and monitor coronary disease non-invasively.
Language:
Chinese
Title:
Cardiovascular Responses to Lower Body Negative Pressure (LBNP) in Healthy Females of Different Physical Fitness
Document ID:
20080020478
Report #:
None
Sales Agency:
Other Sources Copyright
Author(s):
Lu, Li-li (Institute of Space Medico-Engineering) Wu, Bin (Institute of Space Medico-Engineering) Huang, Wei-fen (Institute of Space Medico-Engineering) Gu, Zhi-ming (Institute of Space Medico-Engineering) Wang, Yan-lei (Institute of Space Medico-Engineering) Liu, Xing-hua (Institute of Space Medico-Engineering) Tang, Yun (Institute of Space Medico-Engineering) Mo, Yan (Institute of Space Medico-Engineering)
Journal:
Space Medicine and Medical Engineering, Volume 20, No. 6, Page: 398-401
Published:
20071201
Source:
Institute of Space Medico-Engineering (Beijing, China)
Pages:
--
Contract #:
None
Abstract:
Proposed to compare responses of tolerance to lower body negative pressure (LBNP) in healthy women of different fitness levels. V02max was examined using a treadmill and a step-wise LBNP procedure to the maximum of -50 mmHg was applied. Twenty one healthy female volunteers were divided into group A, sitting employees (n=11, V02max 33.69 +/- 4.50 mL kg(exp -1) min(exp -1) and group B, pilots (n=10, V02max 39.61 +/- 3.84 mL kg(exp -1) min(exp -1). With the step-wise of LBNP, heart rate of all groups were gradually increased. Under -50 mmHg, heart rate (HR) increased significantly (P<0.01 to approximately 0.001), systolic blood pressure (SBP) of group B decreased significantly (P<0.01), diastolic blood pressure (DBP) of group A increased significantly (P<0.05) and mean blood pressure (MBP) of group B decreased significantly (P<0.05). It is indicated that those with better fitness have lower cardiovascular responses to LBNP.
Language:
Chinese
52-02 CLINICAL MEDICINE
Jun 29, 2008 -- Additions to the NASA scientific and technical information knowledge base
Title:
Space Medicine and Medical Engineering, Volume 20, No. 6
Document ID:
20080020461
Report #:
CN-11-2774/R
Sales Agency:
Other Sources Copyright
Author(s):
Wang, Yong-zhi (Institute of Space Medico-Engineering) Grigoriev, A. I. (Institute of Space Medico-Engineering) White, Ronald J. (Institute of Space Medico-Engineering) Wang, Xi-ji (Institute of Space Medico-Engineering) Yu, Meng-sun (Institute of Space Medico-Engineering) QI Fa-ren (Institute of Space Medico-Engineering) Wei, Jin-he (Institute of Space Medico-Engineering) Chen, Shan-guang (Institute of Space Medico-Engineering) Wang, Xian-min (Institute of Space Medico-Engineering) Bai, Jing (Institute of Space Medico-Engineering) Bai, Yan-qiang (Institute of Space Medico-Engineering) Sun, Xi-qing (Institute of Space Medico-Engineering) Hong, Feng (Institute of Space Medico-Engineering) Su Hong-yu (Institute of Space Medico-Engineering) Jiang, Shi-zhong (Institute of Space Medico-Engineering)
Published:
20071201 Publisher: Institute of Space Medico-Engineering
Source:
Institute of Space Medico-Engineering (Beijing, China)
Pages:
100
Contract #:
None
Abstract:
Topics covered include: Identification of Model Parameters Basing on Matched Processing between Simulated and Recorded sEMG Signals; Cardiovascular Responses to Lower Body Negative Pressure (LBNP) in Healthy Females of Different Physical Fitness; Protective Effects of Cudrania Tricuspidata Polysaccharides and Lycium Barbarium; Polysaccharides on the Immune Function of Tail-suspended Mice; Effects of Simulated Weightlessness on Cellular Morphology, Cell Multiplication and Cell Cycle of MG-63 Cell; Effects of Heat Stress on Exercise Tolerance, Serum Testosterone and Cortisol; Concentrations in Tail-Suspended Rats; Alteration of Fos Expression in Periaqueductal Gray of Rat after 2 Weeks Simulated Weightlessness; Effects of Carbon Monoxide on Cerebella Gene Expression in Mice; Design of a Head-up Tilt Experimental System for Measuring Head Blood Pressure and Its Dynamic Process; The Design and Experiment of Solid Polymer Electrolyte Water Electrolytic Cell; A Study of Metal Oxide CO2 Absorbents; A Study of Computer Detecting Methods for Animal Swimming Experiment; Facial Skin Temperature Increase Induced by Local Cooling of Jugular Vessel and Its Interpretation Using Systematic Bioheat Transfer Mechanism; EEG Study on Transcutaneous Electrical Acupoint Stimulation as a Fatigue Countermeasure; Estimation of Mean Trabecular Bone Spacing Using Cepstrum Method Based on Inverse Filter; Detrended Fluctuation Analysis of Pulse Rate Variability Signals of Coronary Disease Patients; Automatic Sleep Stage Classification Based on Hilbert-Huang Transform Method of EEG; and Progress in Fabrication of Neural Probe Microelectrodes and Its Application in Brain-Machine Interface.
Language:
English
Title:
Estimation of Mean Trabecular Bone Spacing Using Cepstrum Method Based on Inverse Filter
Document ID:
20080020462
Report #:
None
Sales Agency:
Other Sources Copyright
Author(s):
Huang, Kai (Institute of Space Medico-Engineering) Ta, De-an (Institute of Space Medico-Engineering) Wang, Wei-qi (Institute of Space Medico-Engineering) Lawrence, HL (Institute of Space Medico-Engineering)
Journal:
Space Medicine and Medical Engineering, Volume 20, No. 6, Page: 451-454
Published:
20071201
Source:
Institute of Space Medico-Engineering (Beijing, China)
Pages:
--
Contract #:
None
Abstract:
Proposed to explore the feasibility of estimating mean trabecular bone spacing (MTBS) by the improved cepstrum method. The improved cepstrum method based on an inverse filter is proposed in this paper. In order to test its performance, simulations were performed and bovine tibia cancellous bone specimens in vitro were used in our experiments. It is indicated that the improved cepstrum method can minimize the influence of transducer impulse response and tissue scatterer properties. It also can be easily implemented with little computation. Compared with traditional cepstrum, the improved cepstrum method has a more accurate MTBS estimate because of its less sensitivity to the variety of MTBS, diffuse scattering and noise.
Language:
Chinese
Title:
EEG Study on Transcutaneous Electrical Acupoint Stimulation as a Fatigue Countermeasure
Document ID:
20080020463
Report #:
None
Sales Agency:
Other Sources Copyright
Author(s):
DONG, Jie (Institute of Space Medico-Engineering) LI, Lu-ming (Tsinghua Univ.) HAO, Hong-wei (Institute of Space Medico-Engineering) CHEN, Zhao-yang (Institute of Space Medico-Engineering)
Journal:
Space Medicine and Medical Engineering, Volume 20, No. 6, Page: 447-450
Published:
20071201
Source:
Institute of Space Medico-Engineering (Beijing, China)
Pages:
--
Contract #:
None
Abstract:
Proposed to investigate the action of transcutaneous electrical acupoint stimulation to reduce fatigue, and to evaluate the countermeasure effect. Twelve-channel EEG signals (F3, F2, F4, C3, Cz, C4, P3, Pz, P4, O1, Oz, O21) were recorded in 9 young, healthy male volunteers under three conditions: normal, fatigue and after transcutaneous electrical acupoint stimulation. G values, the average power spectral densities, of delta, theta, alpha, beta EEG bands were calculated to analyze the EEG effect after transcutaneous electrical acupoint stimulation. G values of delta, theta, alpha, beta EEG bands and imbalance of G values of alpha EEG bands increased during fatigue, compared with those in the normal condition. G values of delta, theta, alpha, beta EEG bands and imbalance of G values of alpha EEG bands decreased after transcutaneous electrical acupoint stimulation. Transcutaneous electrical acupoint stimulation provides a positive countermeasure effect for fatigue as revealed by EEG.
Language:
Chinese
Title:
Effects of Simulated Weightlessness on Cellular Morphology, Cell Multiplication and Cell Cycle of MG-63 Cells
Document ID:
20080020465
Report #:
None
Sales Agency:
Other Sources Copyright
Author(s):
Wang, Pan (Institute of Space Medico-Engineering) Zhang, Shu (Institute of Space Medico-Engineering) Wang, Bing (Institute of Space Medico-Engineering) Sun, Xi-qing (Institute of Space Medico-Engineering) Geng, Jie (Institute of Space Medico-Engineering) Gao, Yuan (Institute of Space Medico-Engineering)
Journal:
Space Medicine and Medical Engineering, Volume 20, No. 6, Page: 406-409
Published:
20071201
Source:
Institute of Space Medico-Engineering (Beijing, China)
Pages:
--
Contract #:
None
Abstract:
Proposed to investigate the effects of simulated weightlessness on cell area, cell multiplication and cell cycle of MG-63 cells. The rotating clinostat was used to simulate weightlessness. The change of cell area was measured with image processing and analysis soft (Image J). Cell growth curve was measured with cytometry. The change of cell cycle was examined with a flow cytometer. Compared with control group, the cell area of cell line MG-63 in 24 h,36 h and 48 h durations of rotating group decreased significantly (P<0.05). Compared with 12 h duration, the cell area in 24 h, 36 h and 48 h durations of rotating group decreased significantly (P<0.05). But in control group, cell area of all 4 experimental durations showed no significant difference among each other. Compared with control group, cell growth curve revealed that cell multiplication was inhibited in rotating group. Compared with control group, the cell cycles of cell line MG-63 in 12 h, 36 h, 48 h sections of rotating group did not change significantly, but the cell in 24 h duration of rotating group was decreased significantly (P<0.05) in G0 + G1 phase and increased significantly (P<0.05 ) in S phase. Simulated weightlessness in rotating clinostat may lead cell area of cell line MG-63 in 24 h, 36 h and 48 h durations to be decreased. Cell multiplication is inhibited in 12 h, 24 h, 36 h and 48 h durations. The conversion of cell from S phase to G2 phase is inhibited in 24 h duration.
Language:
Chinese
Title:
A Study of Computer Detecting Methods for Animal Swimming Experiment
Document ID:
20080020468
Report #:
None
Sales Agency:
Other Sources Copyright
Author(s):
ZHANG, Yu (Institute of Space Medico-Engineering) CHEN, Shang-guang (Institute of Space Medico-Engineering) LI, Da-chen (Institute of Space Medico-Engineering)
Journal:
Space Medicine and Medical Engineering, Volume 20, No. 6, Page: 436-440
Published:
20071201
Source:
Institute of Space Medico-Engineering (Beijing, China)
Pages:
--
Contract #:
None
Abstract:
Proposed to study a a computer-based testing system for an animal swimming test with mice by integrating the knowledge of computer science and image processing with that of traditional Chinese medicine. The moving objects of the swimming mice were extracted by computer and the gained information was analyzed. The computer controlled animal swimming testing system was developed and a new index-evaluation method which is more sensitive to mice swimming resistance were established. The computer detecting method yielded higher automation and more samples to be detected, obtained more detecting indices and more comprehensive and accurate data providing a new effective measure for the animal swimming experiment in the pharmacological research of Chinese medicinal herbs.
Language:
Chinese
Title:
Automatic Sleep Stage Classification Based on Hilbert-Huang Transform Method of EEG
Document ID:
20080020470
Report #:
None
Sales Agency:
Other Sources Copyright
Author(s):
Li, Gu (Institute of Space Medico-Engineering) Fan, Ying-le (Institute of Space Medico-Engineering) Li, Yi (Institute of Space Medico-Engineering) PANG, Quan (Institute of Space Medico-Engineering)
Journal:
Space Medicine and Medical Engineering, Volume 20, No. 6, Page: 458-463
Published:
20071201
Source:
Institute of Space Medico-Engineering (Beijing, China)
Pages:
--
Contract #:
None
Abstract:
Proposed to present a new application of the Hilbert-Huang transform method for automatic sleep stage classification. Instantaneous frequencies of sleep EEG with physical meaning and energy-frequency distribution used as feature parameters for each stage were computed with the Hilbert-Huang transform. Finally, the pattern recognition method of nearest neighbors was applied to optimal classification. Five hundred and sixty samples were picked from sleep EEG, and classification was made. The mean rate of accuracy was as high as 81.7%. Automatic sleep stage classification can be made effectively from features of sleep EEG by the Hilbert-Huang transform.
Language:
English
Title:
Design of a Head-up Tilt Experimental System for Measuring Head Blood Pressure and Its Dynamic Process
Document ID:
20080020473
Report #:
None
Sales Agency:
Other Sources Copyright
Author(s):
LIU, Yan-yong (Institute of Space Medico-Engineering) YU, Meng-sun (Air Force Inst. of Aviation Medicine) XIANG, Hai-yan (Institute of Space Medico-Engineering) JI, Jun (Institute of Space Medico-Engineering) Li, Yin-hua (Institute of Space Medico-Engineering) QIN, Yu-fei (Institute of Space Medico-Engineering)
Journal:
Space Medicine and Medical Engineering, Volume 20, No. 6, Page: 422-426
Published:
20071201
Source:
Institute of Space Medico-Engineering (Beijing, China)
Pages:
--
Contract #:
None
Abstract:
Proposed to design a head-up tilt (HUT) experimental system which is capable of measuring head blood pressure and its dynamic process, to enhance the efficiency of a HUT experiment. The head blood pressure was calculated by the individual-calibrated pulse wave transit time (PWTT) measured from the B point of the impedance cardiography (ICG) to the beginning point of the superficial temporal artery pulse wave. Based on the improved tilt bed, the HUT experimental system was designed to detect the dynamic blood pressure, ECG, phonocardiogram (PCG), respiration and ICG continuously. Finally, the system performance was examined by HUT experiments of three volunteers. Head blood pressure was calibrated with individual precise PWTT. The system detected physiological signals continuously and stably during HUT experiments and our preliminary results presented the minimum value, dynamic regulating process and overall level of head blood pressure. The system can exactly describe continuous, dynamic and transient process of head blood pressure during HUT experiments, which will provide more information about the regulation function of the cardiovascular system. It is possible to study the instant responses of the pilot to + Gz stresses in high-perfomance aircraft.
Language:
Chinese
Title:
Detrended Fluctuation Analysis of Pulse Rate Variability Signals of Coronary Disease Patients
Document ID:
20080020475
Report #:
None
Sales Agency:
Other Sources Copyright
Author(s):
Zhao, Hai-yong (Institute of Space Medico-Engineering) Qiu, Yi-hong (Institute of Space Medico-Engineering) Hu, Si-jun (Institute of Space Medico-Engineering) Zhu, Yi-sheng (Institute of Space Medico-Engineering)
Journal:
Space Medicine and Medical Engineering, Volume 20, No. 6, Page: 455-457
Published:
20071201
Source:
Institute of Space Medico-Engineering (Beijing, China)
Pages:
--
Contract #:
None
Abstract:
Nonlinear method was applied to the analysis of pulse rate variability (PRV) signal of healthy people and coronary disease patients to find the different features, which can be used to detect coronary disease invasively and monitor the process of the disease. Pulse waves of the healthy people and patients (18 subjects in each group) were sampled by photoplethysmographic (PPG) sensor. The detrended fluctuation analysis algorithm was applied to PRV series which extracted from PPG signals, and the scaling exponents of the two groups of signals were obtained. The average scaling exponents of the patients, i.e. short term alpha(exp 1) long term alpha(exp 2), and whole process alpha, were significantly lower than those of the healthy subjects. Detrended fluctuation analysis algorithm was applied to the PRV signal of the healthy subjects and coronary disease patients. It was found that the average scaling exponents of the patients, alpha(exp 1) , alpha(exp 2) and alpha, are significantly different from those of the healthy people. These findings suggest that a nonlinear index could be used to detect and monitor coronary disease non-invasively.
Language:
Chinese
Title:
Cardiovascular Responses to Lower Body Negative Pressure (LBNP) in Healthy Females of Different Physical Fitness
Document ID:
20080020478
Report #:
None
Sales Agency:
Other Sources Copyright
Author(s):
Lu, Li-li (Institute of Space Medico-Engineering) Wu, Bin (Institute of Space Medico-Engineering) Huang, Wei-fen (Institute of Space Medico-Engineering) Gu, Zhi-ming (Institute of Space Medico-Engineering) Wang, Yan-lei (Institute of Space Medico-Engineering) Liu, Xing-hua (Institute of Space Medico-Engineering) Tang, Yun (Institute of Space Medico-Engineering) Mo, Yan (Institute of Space Medico-Engineering)
Journal:
Space Medicine and Medical Engineering, Volume 20, No. 6, Page: 398-401
Published:
20071201
Source:
Institute of Space Medico-Engineering (Beijing, China)
Pages:
--
Contract #:
None
Abstract:
Proposed to compare responses of tolerance to lower body negative pressure (LBNP) in healthy women of different fitness levels. V02max was examined using a treadmill and a step-wise LBNP procedure to the maximum of -50 mmHg was applied. Twenty one healthy female volunteers were divided into group A, sitting employees (n=11, V02max 33.69 +/- 4.50 mL kg(exp -1) min(exp -1) and group B, pilots (n=10, V02max 39.61 +/- 3.84 mL kg(exp -1) min(exp -1). With the step-wise of LBNP, heart rate of all groups were gradually increased. Under -50 mmHg, heart rate (HR) increased significantly (P<0.01 to approximately 0.001), systolic blood pressure (SBP) of group B decreased significantly (P<0.01), diastolic blood pressure (DBP) of group A increased significantly (P<0.05) and mean blood pressure (MBP) of group B decreased significantly (P<0.05). It is indicated that those with better fitness have lower cardiovascular responses to LBNP.
Language:
Chinese
52-03 PHYSIOLOGICAL FACTORS
Jun 29, 2008 -- Additions to the NASA scientific and technical information knowledge base
Title:
Space Medicine and Medical Engineering, Volume 20, No. 6
Document ID:
20080020461
Report #:
CN-11-2774/R
Sales Agency:
Other Sources Copyright
Author(s):
Wang, Yong-zhi (Institute of Space Medico-Engineering) Grigoriev, A. I. (Institute of Space Medico-Engineering) White, Ronald J. (Institute of Space Medico-Engineering) Wang, Xi-ji (Institute of Space Medico-Engineering) Yu, Meng-sun (Institute of Space Medico-Engineering) QI Fa-ren (Institute of Space Medico-Engineering) Wei, Jin-he (Institute of Space Medico-Engineering) Chen, Shan-guang (Institute of Space Medico-Engineering) Wang, Xian-min (Institute of Space Medico-Engineering) Bai, Jing (Institute of Space Medico-Engineering) Bai, Yan-qiang (Institute of Space Medico-Engineering) Sun, Xi-qing (Institute of Space Medico-Engineering) Hong, Feng (Institute of Space Medico-Engineering) Su Hong-yu (Institute of Space Medico-Engineering) Jiang, Shi-zhong (Institute of Space Medico-Engineering)
Published:
20071201 Publisher: Institute of Space Medico-Engineering
Source:
Institute of Space Medico-Engineering (Beijing, China)
Pages:
100
Contract #:
None
Abstract:
Topics covered include: Identification of Model Parameters Basing on Matched Processing between Simulated and Recorded sEMG Signals; Cardiovascular Responses to Lower Body Negative Pressure (LBNP) in Healthy Females of Different Physical Fitness; Protective Effects of Cudrania Tricuspidata Polysaccharides and Lycium Barbarium; Polysaccharides on the Immune Function of Tail-suspended Mice; Effects of Simulated Weightlessness on Cellular Morphology, Cell Multiplication and Cell Cycle of MG-63 Cell; Effects of Heat Stress on Exercise Tolerance, Serum Testosterone and Cortisol; Concentrations in Tail-Suspended Rats; Alteration of Fos Expression in Periaqueductal Gray of Rat after 2 Weeks Simulated Weightlessness; Effects of Carbon Monoxide on Cerebella Gene Expression in Mice; Design of a Head-up Tilt Experimental System for Measuring Head Blood Pressure and Its Dynamic Process; The Design and Experiment of Solid Polymer Electrolyte Water Electrolytic Cell; A Study of Metal Oxide CO2 Absorbents; A Study of Computer Detecting Methods for Animal Swimming Experiment; Facial Skin Temperature Increase Induced by Local Cooling of Jugular Vessel and Its Interpretation Using Systematic Bioheat Transfer Mechanism; EEG Study on Transcutaneous Electrical Acupoint Stimulation as a Fatigue Countermeasure; Estimation of Mean Trabecular Bone Spacing Using Cepstrum Method Based on Inverse Filter; Detrended Fluctuation Analysis of Pulse Rate Variability Signals of Coronary Disease Patients; Automatic Sleep Stage Classification Based on Hilbert-Huang Transform Method of EEG; and Progress in Fabrication of Neural Probe Microelectrodes and Its Application in Brain-Machine Interface.
Language:
English
Title:
Estimation of Mean Trabecular Bone Spacing Using Cepstrum Method Based on Inverse Filter
Document ID:
20080020462
Report #:
None
Sales Agency:
Other Sources Copyright
Author(s):
Huang, Kai (Institute of Space Medico-Engineering) Ta, De-an (Institute of Space Medico-Engineering) Wang, Wei-qi (Institute of Space Medico-Engineering) Lawrence, HL (Institute of Space Medico-Engineering)
Journal:
Space Medicine and Medical Engineering, Volume 20, No. 6, Page: 451-454
Published:
20071201
Source:
Institute of Space Medico-Engineering (Beijing, China)
Pages:
--
Contract #:
None
Abstract:
Proposed to explore the feasibility of estimating mean trabecular bone spacing (MTBS) by the improved cepstrum method. The improved cepstrum method based on an inverse filter is proposed in this paper. In order to test its performance, simulations were performed and bovine tibia cancellous bone specimens in vitro were used in our experiments. It is indicated that the improved cepstrum method can minimize the influence of transducer impulse response and tissue scatterer properties. It also can be easily implemented with little computation. Compared with traditional cepstrum, the improved cepstrum method has a more accurate MTBS estimate because of its less sensitivity to the variety of MTBS, diffuse scattering and noise.
Language:
Chinese
Title:
EEG Study on Transcutaneous Electrical Acupoint Stimulation as a Fatigue Countermeasure
Document ID:
20080020463
Report #:
None
Sales Agency:
Other Sources Copyright
Author(s):
DONG, Jie (Institute of Space Medico-Engineering) LI, Lu-ming (Tsinghua Univ.) HAO, Hong-wei (Institute of Space Medico-Engineering) CHEN, Zhao-yang (Institute of Space Medico-Engineering)
Journal:
Space Medicine and Medical Engineering, Volume 20, No. 6, Page: 447-450
Published:
20071201
Source:
Institute of Space Medico-Engineering (Beijing, China)
Pages:
--
Contract #:
None
Abstract:
Proposed to investigate the action of transcutaneous electrical acupoint stimulation to reduce fatigue, and to evaluate the countermeasure effect. Twelve-channel EEG signals (F3, F2, F4, C3, Cz, C4, P3, Pz, P4, O1, Oz, O21) were recorded in 9 young, healthy male volunteers under three conditions: normal, fatigue and after transcutaneous electrical acupoint stimulation. G values, the average power spectral densities, of delta, theta, alpha, beta EEG bands were calculated to analyze the EEG effect after transcutaneous electrical acupoint stimulation. G values of delta, theta, alpha, beta EEG bands and imbalance of G values of alpha EEG bands increased during fatigue, compared with those in the normal condition. G values of delta, theta, alpha, beta EEG bands and imbalance of G values of alpha EEG bands decreased after transcutaneous electrical acupoint stimulation. Transcutaneous electrical acupoint stimulation provides a positive countermeasure effect for fatigue as revealed by EEG.
Language:
Chinese
Title:
Effects of Heat Stress on Exercise Tolerance, Serum Testosterone and Cortisol Concentrations in Tail-Suspended Rats
Document ID:
20080020464
Report #:
None
Sales Agency:
Other Sources Copyright
Author(s):
YANG, Zhen-zhong (Institute of Space Medico-Engineering) YU, Xue-jun (China Astronaut Research and Training Center) FEI, Jin-xue (Institute of Space Medico-Engineering) GAO, Yu-chen (Institute of Space Medico-Engineering) WANG, Hong-hui (Institute of Space Medico-Engineering)
Journal:
Space Medicine and Medical Engineering, Volume 20, No. 6, Page: 410-413
Published:
20071201
Source:
Institute of Space Medico-Engineering (Beijing, China)
Pages:
--
Contract #:
None
Abstract:
Proposed to investigate the effects of heat stress on exercise tolerance and functions of protein metabolism changes in tail-suspended rats. Forty-six male SD rats were randomly assigned to 4 groups: exercise control group (Con) , exercise after tail-suspension group (ES), exercise under high temperature group (EHT) and exercise under high temperature after tail-suspension group (EHTS). The rats underwent exercise of increasing intensity until exhaustion under normal or 38 C environment after 14 d of tail suspension or Con. The running time and the increased rectal temperature after exercise were measured at the end of exhaustion. Blood samples were collected immediately after exercise to detect serum testosterone and cortisol concentrations. As compared with Con rats, the running time, serum testosterone concentrations and testosterone/cortisol ratio of ES rats, EHT and EHTS rats decreased significantly. As compared with Con rats, the serum cortisol concentrations showed no significant change in ES and EHT rats, and the concentrations increased significantly in EHTS rats. Running time, serum testosterone concentrations and testosterone/cortisol ratio of EHTS rats were significantly shorter or lower when compared with those of ES rats. The increases of rectal temperature and serum cortisol concentrations in EHTS rats were significantly higher than those in ES rats. Thermal stress(38 C) significantly decreases the exercise tolerance of tail-suspended rats, which might be related to the decrease of thermoregulation capability, intensification of catabolism and attenuation of anabolism.
Language:
Chinese
Title:
Design of a Head-up Tilt Experimental System for Measuring Head Blood Pressure and Its Dynamic Process
Document ID:
20080020473
Report #:
None
Sales Agency:
Other Sources Copyright
Author(s):
LIU, Yan-yong (Institute of Space Medico-Engineering) YU, Meng-sun (Air Force Inst. of Aviation Medicine) XIANG, Hai-yan (Institute of Space Medico-Engineering) JI, Jun (Institute of Space Medico-Engineering) Li, Yin-hua (Institute of Space Medico-Engineering) QIN, Yu-fei (Institute of Space Medico-Engineering)
Journal:
Space Medicine and Medical Engineering, Volume 20, No. 6, Page: 422-426
Published:
20071201
Source:
Institute of Space Medico-Engineering (Beijing, China)
Pages:
--
Contract #:
None
Abstract:
Proposed to design a head-up tilt (HUT) experimental system which is capable of measuring head blood pressure and its dynamic process, to enhance the efficiency of a HUT experiment. The head blood pressure was calculated by the individual-calibrated pulse wave transit time (PWTT) measured from the B point of the impedance cardiography (ICG) to the beginning point of the superficial temporal artery pulse wave. Based on the improved tilt bed, the HUT experimental system was designed to detect the dynamic blood pressure, ECG, phonocardiogram (PCG), respiration and ICG continuously. Finally, the system performance was examined by HUT experiments of three volunteers. Head blood pressure was calibrated with individual precise PWTT. The system detected physiological signals continuously and stably during HUT experiments and our preliminary results presented the minimum value, dynamic regulating process and overall level of head blood pressure. The system can exactly describe continuous, dynamic and transient process of head blood pressure during HUT experiments, which will provide more information about the regulation function of the cardiovascular system. It is possible to study the instant responses of the pilot to + Gz stresses in high-perfomance aircraft.
Language:
Chinese
Title:
Identification of Model Parameters Basing on Matched Processing between Simulated and Recorded sEMG Signals
Document ID:
20080020477
Report #:
None
Sales Agency:
Other Sources Copyright
Author(s):
Li, Qiang (University of Science and Technology) Yang, Ji-hai (University of Science and Technology) Zhao, Zhang-yan (University of Science and Technology) Chue, Xue-zhong (University of Science and Technology) Chen, Xiang (University of Science and Technology) Lou, Zhi (University of Science and Technology)
Journal:
Space Medicine and Medical Engineering, Volume 20, No. 6, Page: 391-397
Published:
20071201
Source:
University of Science and Technology (Hefei Anhui, China)
Pages:
--
Contract #:
None
Abstract:
Proposed to identify the model parameters of surface Electromyography (sEMG) by comparison between simulated and recorded signals. A physiological model of sEMG signal was established basing on several logical hypothetical conditions, such as motor unit action potentials (MUAP), motor unit recruitment and firing behavior caused by excitation, architecture of volume conductor and other simulated factors. According to the matched shapes between the simulated and recorded sEMG signals, a group of model parameters was obtained; according to the similar power spectrum variations of real sEMG signals, decreased muscle fiber conduction velocity (MFCV) was applied to simulate the sEMG signals of the fatigued muscle. The experimental results showed that the simulated superimposed MUAP shapes could be matched with the recorded MUAPs satisfactorily by adjusting some proper physiological parameters of the model. When the MFCV of each fiber was assumed to decrease, the mean and median frequency (MNF, MDF) of the simulated sEMG signals declined, and this phenomenon was very similar to that of the recorded sEMG signals and could be used to interpret the muscle fatigue process. This model provides an effective approach to simulate real sEMG signals, and the simulated signals can also be used to help the analysis of recorded sEMG signals.
Language:
English
Title:
Cardiovascular Responses to Lower Body Negative Pressure (LBNP) in Healthy Females of Different Physical Fitness
Document ID:
20080020478
Report #:
None
Sales Agency:
Other Sources Copyright
Author(s):
Lu, Li-li (Institute of Space Medico-Engineering) Wu, Bin (Institute of Space Medico-Engineering) Huang, Wei-fen (Institute of Space Medico-Engineering) Gu, Zhi-ming (Institute of Space Medico-Engineering) Wang, Yan-lei (Institute of Space Medico-Engineering) Liu, Xing-hua (Institute of Space Medico-Engineering) Tang, Yun (Institute of Space Medico-Engineering) Mo, Yan (Institute of Space Medico-Engineering)
Journal:
Space Medicine and Medical Engineering, Volume 20, No. 6, Page: 398-401
Published:
20071201
Source:
Institute of Space Medico-Engineering (Beijing, China)
Pages:
--
Contract #:
None
Abstract:
Proposed to compare responses of tolerance to lower body negative pressure (LBNP) in healthy women of different fitness levels. V02max was examined using a treadmill and a step-wise LBNP procedure to the maximum of -50 mmHg was applied. Twenty one healthy female volunteers were divided into group A, sitting employees (n=11, V02max 33.69 +/- 4.50 mL kg(exp -1) min(exp -1) and group B, pilots (n=10, V02max 39.61 +/- 3.84 mL kg(exp -1) min(exp -1). With the step-wise of LBNP, heart rate of all groups were gradually increased. Under -50 mmHg, heart rate (HR) increased significantly (P<0.01 to approximately 0.001), systolic blood pressure (SBP) of group B decreased significantly (P<0.01), diastolic blood pressure (DBP) of group A increased significantly (P<0.05) and mean blood pressure (MBP) of group B decreased significantly (P<0.05). It is indicated that those with better fitness have lower cardiovascular responses to LBNP.
Language:
Chinese
52-04 BIOLOGICAL RADIATION EFFECTS
Jun 29, 2008 -- Additions to the NASA scientific and technical information knowledge base
No records are available for this topic on this date.
53-01 PSYCHOLOGICAL FACTORS
Jun 29, 2008 -- Additions to the NASA scientific and technical information knowledge base
No records are available for this topic on this date.
54-02 CREW SAFETY AND PROTECTIVE CLOTHING
Jun 29, 2008 -- Additions to the NASA scientific and technical information knowledge base
No records are available for this topic on this date.
54-03 HUMAN ENGINEERING
Jun 29, 2008 -- Additions to the NASA scientific and technical information knowledge base
Title:
Effects of Simulated Weightlessness on Cellular Morphology, Cell Multiplication and Cell Cycle of MG-63 Cells
Document ID:
20080020465
Report #:
None
Sales Agency:
Other Sources Copyright
Author(s):
Wang, Pan (Institute of Space Medico-Engineering) Zhang, Shu (Institute of Space Medico-Engineering) Wang, Bing (Institute of Space Medico-Engineering) Sun, Xi-qing (Institute of Space Medico-Engineering) Geng, Jie (Institute of Space Medico-Engineering) Gao, Yuan (Institute of Space Medico-Engineering)
Journal:
Space Medicine and Medical Engineering, Volume 20, No. 6, Page: 406-409
Published:
20071201
Source:
Institute of Space Medico-Engineering (Beijing, China)
Pages:
--
Contract #:
None
Abstract:
Proposed to investigate the effects of simulated weightlessness on cell area, cell multiplication and cell cycle of MG-63 cells. The rotating clinostat was used to simulate weightlessness. The change of cell area was measured with image processing and analysis soft (Image J). Cell growth curve was measured with cytometry. The change of cell cycle was examined with a flow cytometer. Compared with control group, the cell area of cell line MG-63 in 24 h,36 h and 48 h durations of rotating group decreased significantly (P<0.05). Compared with 12 h duration, the cell area in 24 h, 36 h and 48 h durations of rotating group decreased significantly (P<0.05). But in control group, cell area of all 4 experimental durations showed no significant difference among each other. Compared with control group, cell growth curve revealed that cell multiplication was inhibited in rotating group. Compared with control group, the cell cycles of cell line MG-63 in 12 h, 36 h, 48 h sections of rotating group did not change significantly, but the cell in 24 h duration of rotating group was decreased significantly (P<0.05) in G0 + G1 phase and increased significantly (P<0.05 ) in S phase. Simulated weightlessness in rotating clinostat may lead cell area of cell line MG-63 in 24 h, 36 h and 48 h durations to be decreased. Cell multiplication is inhibited in 12 h, 24 h, 36 h and 48 h durations. The conversion of cell from S phase to G2 phase is inhibited in 24 h duration.
Language:
Chinese
Title:
Progress in Fabrication of Neural Probe Microelectrodes and its Application in Brain-Machine Interface
Document ID:
20080020471
Report #:
None
Sales Agency:
Other Sources Copyright
Author(s):
Yao, Yuan (Institute of Space Medico-Engineering) Li, Gang (Institute of Space Medico-Engineering) Jin, Qing-hui (Institute of Space Medico-Engineering) Zhao, Jian-long (Institute of Space Medico-Engineering)
Journal:
Space Medicine and Medical Engineering, Volume 20, No. 6, Page: 464-468
Published:
20071201
Source:
Institute of Space Medico-Engineering (Beijing, China)
Pages:
--
Contract #:
None
Abstract:
Recently, implantable neural microelectrodes has been a new, exciting field in neural science and microelectronics. In this paper, the development and current status of techniques for fabricating the neural probe microelectrode and its applications in brain-machine interface were reviewed in detail, the characteristics and limitations of various methods for fabricating probe microelectrodes were discussed and progress and further investigations in this area were reviewed.
Language:
English
54-04 MAN-MACHINE SYSTEMS
Jun 29, 2008 -- Additions to the NASA scientific and technical information knowledge base
Title:
Progress in Fabrication of Neural Probe Microelectrodes and its Application in Brain-Machine Interface
Document ID:
20080020471
Report #:
None
Sales Agency:
Other Sources Copyright
Author(s):
Yao, Yuan (Institute of Space Medico-Engineering) Li, Gang (Institute of Space Medico-Engineering) Jin, Qing-hui (Institute of Space Medico-Engineering) Zhao, Jian-long (Institute of Space Medico-Engineering)
Journal:
Space Medicine and Medical Engineering, Volume 20, No. 6, Page: 464-468
Published:
20071201
Source:
Institute of Space Medico-Engineering (Beijing, China)
Pages:
--
Contract #:
None
Abstract:
Recently, implantable neural microelectrodes has been a new, exciting field in neural science and microelectronics. In this paper, the development and current status of techniques for fabricating the neural probe microelectrode and its applications in brain-machine interface were reviewed in detail, the characteristics and limitations of various methods for fabricating probe microelectrodes were discussed and progress and further investigations in this area were reviewed.
Language:
English
54-05 BIOINSTRUMENTATION
Jun 29, 2008 -- Additions to the NASA scientific and technical information knowledge base
Title:
Space Medicine and Medical Engineering, Volume 20, No. 6
Document ID:
20080020461
Report #:
CN-11-2774/R
Sales Agency:
Other Sources Copyright
Author(s):
Wang, Yong-zhi (Institute of Space Medico-Engineering) Grigoriev, A. I. (Institute of Space Medico-Engineering) White, Ronald J. (Institute of Space Medico-Engineering) Wang, Xi-ji (Institute of Space Medico-Engineering) Yu, Meng-sun (Institute of Space Medico-Engineering) QI Fa-ren (Institute of Space Medico-Engineering) Wei, Jin-he (Institute of Space Medico-Engineering) Chen, Shan-guang (Institute of Space Medico-Engineering) Wang, Xian-min (Institute of Space Medico-Engineering) Bai, Jing (Institute of Space Medico-Engineering) Bai, Yan-qiang (Institute of Space Medico-Engineering) Sun, Xi-qing (Institute of Space Medico-Engineering) Hong, Feng (Institute of Space Medico-Engineering) Su Hong-yu (Institute of Space Medico-Engineering) Jiang, Shi-zhong (Institute of Space Medico-Engineering)
Published:
20071201 Publisher: Institute of Space Medico-Engineering
Source:
Institute of Space Medico-Engineering (Beijing, China)
Pages:
100
Contract #:
None
Abstract:
Topics covered include: Identification of Model Parameters Basing on Matched Processing between Simulated and Recorded sEMG Signals; Cardiovascular Responses to Lower Body Negative Pressure (LBNP) in Healthy Females of Different Physical Fitness; Protective Effects of Cudrania Tricuspidata Polysaccharides and Lycium Barbarium; Polysaccharides on the Immune Function of Tail-suspended Mice; Effects of Simulated Weightlessness on Cellular Morphology, Cell Multiplication and Cell Cycle of MG-63 Cell; Effects of Heat Stress on Exercise Tolerance, Serum Testosterone and Cortisol; Concentrations in Tail-Suspended Rats; Alteration of Fos Expression in Periaqueductal Gray of Rat after 2 Weeks Simulated Weightlessness; Effects of Carbon Monoxide on Cerebella Gene Expression in Mice; Design of a Head-up Tilt Experimental System for Measuring Head Blood Pressure and Its Dynamic Process; The Design and Experiment of Solid Polymer Electrolyte Water Electrolytic Cell; A Study of Metal Oxide CO2 Absorbents; A Study of Computer Detecting Methods for Animal Swimming Experiment; Facial Skin Temperature Increase Induced by Local Cooling of Jugular Vessel and Its Interpretation Using Systematic Bioheat Transfer Mechanism; EEG Study on Transcutaneous Electrical Acupoint Stimulation as a Fatigue Countermeasure; Estimation of Mean Trabecular Bone Spacing Using Cepstrum Method Based on Inverse Filter; Detrended Fluctuation Analysis of Pulse Rate Variability Signals of Coronary Disease Patients; Automatic Sleep Stage Classification Based on Hilbert-Huang Transform Method of EEG; and Progress in Fabrication of Neural Probe Microelectrodes and Its Application in Brain-Machine Interface.
Language:
English
Title:
EEG Study on Transcutaneous Electrical Acupoint Stimulation as a Fatigue Countermeasure
Document ID:
20080020463
Report #:
None
Sales Agency:
Other Sources Copyright
Author(s):
DONG, Jie (Institute of Space Medico-Engineering) LI, Lu-ming (Tsinghua Univ.) HAO, Hong-wei (Institute of Space Medico-Engineering) CHEN, Zhao-yang (Institute of Space Medico-Engineering)
Journal:
Space Medicine and Medical Engineering, Volume 20, No. 6, Page: 447-450
Published:
20071201
Source:
Institute of Space Medico-Engineering (Beijing, China)
Pages:
--
Contract #:
None
Abstract:
Proposed to investigate the action of transcutaneous electrical acupoint stimulation to reduce fatigue, and to evaluate the countermeasure effect. Twelve-channel EEG signals (F3, F2, F4, C3, Cz, C4, P3, Pz, P4, O1, Oz, O21) were recorded in 9 young, healthy male volunteers under three conditions: normal, fatigue and after transcutaneous electrical acupoint stimulation. G values, the average power spectral densities, of delta, theta, alpha, beta EEG bands were calculated to analyze the EEG effect after transcutaneous electrical acupoint stimulation. G values of delta, theta, alpha, beta EEG bands and imbalance of G values of alpha EEG bands increased during fatigue, compared with those in the normal condition. G values of delta, theta, alpha, beta EEG bands and imbalance of G values of alpha EEG bands decreased after transcutaneous electrical acupoint stimulation. Transcutaneous electrical acupoint stimulation provides a positive countermeasure effect for fatigue as revealed by EEG.
Language:
Chinese
Title:
Automatic Sleep Stage Classification Based on Hilbert-Huang Transform Method of EEG
Document ID:
20080020470
Report #:
None
Sales Agency:
Other Sources Copyright
Author(s):
Li, Gu (Institute of Space Medico-Engineering) Fan, Ying-le (Institute of Space Medico-Engineering) Li, Yi (Institute of Space Medico-Engineering) PANG, Quan (Institute of Space Medico-Engineering)
Journal:
Space Medicine and Medical Engineering, Volume 20, No. 6, Page: 458-463
Published:
20071201
Source:
Institute of Space Medico-Engineering (Beijing, China)
Pages:
--
Contract #:
None
Abstract:
Proposed to present a new application of the Hilbert-Huang transform method for automatic sleep stage classification. Instantaneous frequencies of sleep EEG with physical meaning and energy-frequency distribution used as feature parameters for each stage were computed with the Hilbert-Huang transform. Finally, the pattern recognition method of nearest neighbors was applied to optimal classification. Five hundred and sixty samples were picked from sleep EEG, and classification was made. The mean rate of accuracy was as high as 81.7%. Automatic sleep stage classification can be made effectively from features of sleep EEG by the Hilbert-Huang transform.
Language:
English
Title:
Progress in Fabrication of Neural Probe Microelectrodes and its Application in Brain-Machine Interface
Document ID:
20080020471
Report #:
None
Sales Agency:
Other Sources Copyright
Author(s):
Yao, Yuan (Institute of Space Medico-Engineering) Li, Gang (Institute of Space Medico-Engineering) Jin, Qing-hui (Institute of Space Medico-Engineering) Zhao, Jian-long (Institute of Space Medico-Engineering)
Journal:
Space Medicine and Medical Engineering, Volume 20, No. 6, Page: 464-468
Published:
20071201
Source:
Institute of Space Medico-Engineering (Beijing, China)
Pages:
--
Contract #:
None
Abstract:
Recently, implantable neural microelectrodes has been a new, exciting field in neural science and microelectronics. In this paper, the development and current status of techniques for fabricating the neural probe microelectrode and its applications in brain-machine interface were reviewed in detail, the characteristics and limitations of various methods for fabricating probe microelectrodes were discussed and progress and further investigations in this area were reviewed.
Language:
English
Title:
Detrended Fluctuation Analysis of Pulse Rate Variability Signals of Coronary Disease Patients
Document ID:
20080020475
Report #:
None
Sales Agency:
Other Sources Copyright
Author(s):
Zhao, Hai-yong (Institute of Space Medico-Engineering) Qiu, Yi-hong (Institute of Space Medico-Engineering) Hu, Si-jun (Institute of Space Medico-Engineering) Zhu, Yi-sheng (Institute of Space Medico-Engineering)
Journal:
Space Medicine and Medical Engineering, Volume 20, No. 6, Page: 455-457
Published:
20071201
Source:
Institute of Space Medico-Engineering (Beijing, China)
Pages:
--
Contract #:
None
Abstract:
Nonlinear method was applied to the analysis of pulse rate variability (PRV) signal of healthy people and coronary disease patients to find the different features, which can be used to detect coronary disease invasively and monitor the process of the disease. Pulse waves of the healthy people and patients (18 subjects in each group) were sampled by photoplethysmographic (PPG) sensor. The detrended fluctuation analysis algorithm was applied to PRV series which extracted from PPG signals, and the scaling exponents of the two groups of signals were obtained. The average scaling exponents of the patients, i.e. short term alpha(exp 1) long term alpha(exp 2), and whole process alpha, were significantly lower than those of the healthy subjects. Detrended fluctuation analysis algorithm was applied to the PRV signal of the healthy subjects and coronary disease patients. It was found that the average scaling exponents of the patients, alpha(exp 1) , alpha(exp 2) and alpha, are significantly different from those of the healthy people. These findings suggest that a nonlinear index could be used to detect and monitor coronary disease non-invasively.
Language:
Chinese
Title:
Identification of Model Parameters Basing on Matched Processing between Simulated and Recorded sEMG Signals
Document ID:
20080020477
Report #:
None
Sales Agency:
Other Sources Copyright
Author(s):
Li, Qiang (University of Science and Technology) Yang, Ji-hai (University of Science and Technology) Zhao, Zhang-yan (University of Science and Technology) Chue, Xue-zhong (University of Science and Technology) Chen, Xiang (University of Science and Technology) Lou, Zhi (University of Science and Technology)
Journal:
Space Medicine and Medical Engineering, Volume 20, No. 6, Page: 391-397
Published:
20071201
Source:
University of Science and Technology (Hefei Anhui, China)
Pages:
--
Contract #:
None
Abstract:
Proposed to identify the model parameters of surface Electromyography (sEMG) by comparison between simulated and recorded signals. A physiological model of sEMG signal was established basing on several logical hypothetical conditions, such as motor unit action potentials (MUAP), motor unit recruitment and firing behavior caused by excitation, architecture of volume conductor and other simulated factors. According to the matched shapes between the simulated and recorded sEMG signals, a group of model parameters was obtained; according to the similar power spectrum variations of real sEMG signals, decreased muscle fiber conduction velocity (MFCV) was applied to simulate the sEMG signals of the fatigued muscle. The experimental results showed that the simulated superimposed MUAP shapes could be matched with the recorded MUAPs satisfactorily by adjusting some proper physiological parameters of the model. When the MFCV of each fiber was assumed to decrease, the mean and median frequency (MNF, MDF) of the simulated sEMG signals declined, and this phenomenon was very similar to that of the recorded sEMG signals and could be used to interpret the muscle fatigue process. This model provides an effective approach to simulate real sEMG signals, and the simulated signals can also be used to help the analysis of recorded sEMG signals.
Language:
English
54-06 ROBOTICS
Jun 29, 2008 -- Additions to the NASA scientific and technical information knowledge base
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55-01 EXTRATERRESTRIAL LIFE
Jun 29, 2008 -- Additions to the NASA scientific and technical information knowledge base
No records are available for this topic on this date.